In basic research Microdialysis is an indispensable tool for drug discovery. CMA’s solutions are used across the globe by drug developers and researchers to achieve fast and efficient drug discovery. CMA´s vision is: To substantially shorten the time-to-market of drug and research projects by offering a complete and leading portfolio of Microdialysis products. 

Microdialysis is a unique technique to monitor the chemistry of the extracellular space in living tissue. In basic research it is primarily used for In Vivo determinations of endogenous compound changes, drug delivery, PK/PD, bioavailability and bioequivalence.

The Microdialysis probes designed to mimic a blood capillary have a semi-permeable membrane that, when perfused with a physiological salt solution, allows an exchange of compounds from an area of high concentration to an area of low concentration. A representative proportion of molecules from the extracellular fluid is then carried to the probe outlet for collection and analysis.

Follow the Product Links for more information about the CMA Microdialysis pumps used for the fluids infusion and collection. 

For microdialysis research

In basic research Microdialysis is an indispensable tool for drug discovery. CMA’s solutions are used across the globe by drug developers and researchers to achieve fast and efficient drug discovery. CMA´s vision is: To substantially shorten the time-to-market of drug and research projects by offering a complete and leading portfolio of Microdialysis products. 

Microdialysis is a unique technique to monitor the chemistry of the extracellular space in living tissue. In basic research it is primarily used for In Vivo determinations of endogenous compound changes, drug delivery, PK/PD, bioavailability and bioequivalence.

The Microdialysis probe accessories

The Microdialysis probes designed to mimic a blood capillary have a semi-permeable membrane that, when perfused with a physiological salt solution, allows an exchange of compounds from an area of high concentration to an area of low concentration. A representative proportion of molecules from the extracellular fluid is then carried to the probe outlet for collection and analysis.

Follow the Product Links for more information about the accessories relate to CMA Microdialysis probes. 

In basic research Microdialysis is an indispensable tool for drug discovery. CMA’s solutions are used across the globe by drug developers and researchers to achieve fast and efficient drug discovery. CMA´s vision is: To substantially shorten the time-to-market of drug and research projects by offering a complete and leading portfolio of Microdialysis products. 

Microdialysis is a unique technique to monitor the chemistry of the extracellular space in living tissue. In basic research it is primarily used for In Vivo determinations of endogenous compound changes, drug delivery, PK/PD, bioavailability and bioequivalence.

The Microdialysis probes

The Microdialysis probes designed to mimic a blood capillary has a semi-permeable membrane that, when perfused with a physiological salt solution, allows an exchange of compounds from an area of high concentration to an area of low concentration. A representative proportion of molecules from the extracellular fluid is then carried to the probe outlet for collection and analysis.

For over 30 years, Panlab S. L. successfully manufactures and distributes three types of polycarbonate cages, 500 type,1000 type and 1000H type cages.

500-type cage

Type-500 cage for mice, made of makrolon (polycarbonate) composed of:

• Home cage made of makrolon (polycarbonate)
• Home cage internal dimensions: 220 x 220 x 145 mm.
• Basal surface: 500 mm2
• Stackable Home cage and wire lid

See the How to Order Tables for Lids, Lid Dividers and Other options

1000-type cage

Type-1000 cage for mice, made of makrolon (polycarbonate) composed of:

• Home cage made of makrolon (polycarbonate)
• Home cage internal dimensions: 215 x 465 x 145 mm.
• Basal surface: 1000 mm2
• Stackable Home cage and wire lid

See the How to Order Tables for Lids, Lid Dividers and Other options

1000H-type cage (NEW!)

Type-1000H cage for rats, made of makrolon (polycarbonate) composed of:

• Home cage made of makrolon (polycarbonate)
• Home cage internal dimensions: 215 x 465 x 190 mm.
• Basal surface: 1000 mm2
• Stackable Home cage and wire lid

See the How to Order Tables for Lids, Lid Dividers and Other options

How to order

*Stainless Steel is AISI-304

The MouseOx® Pulse Oximeter for Rodents provides real–time, continuous measurements of arterial O2 saturation, pulse strength, breath rate, blood flow, and the effort to breathe.

The new MouseOx®Plus now offers new modules that will expand the system out to measure temperature and optionally expand the system to work with 16 animals! All these measurements are done via a non–invasive sensor that was specially developed to provide accurate measurements for heart rates up to 900 BPM.

The MouseOx®Plus; is ideal for monitoring subjects during surgery — prevent hypoxia, titrate mechanical ventilation, monitor depth of anesthesia, titrate supplemental oxygen, set alarms, and monitor in real-time every breath! Now the MouseOx®Plus allows you to expand out to include optional temperature measurement and the new Multiplexer™ allowing you to collect data on up to 16 animals. A wide range of clips are available to accommodate both awake and anesthetized animals in a variety of applications. The MRI sensor allows safe monitoring while in MRI environment. The CollarClip™ is a non-invasive clip easily applied to monitor freely roaming subjects while the ThroatClip™ allows for monitoring of anesthetized animals. We also offer standard and neonatal sensors that attach to the animal's thigh or foot – increasing the flexibility of this system while maintaining ease of use for the researcher.

The complete system involves the MouseOx®Plus, sensor and software or the Starr-link™ module for your data acquisition system. Additional accessories are available depending on specific application requirements. The MouseOx™ Plus software utilizes WinDaq Waveform Browser. Built-in statistics and filtering capabilities expand the system's flexibility. The waveform and real–time data point for each parameter measured is shown on the software.

FISO is a pioneer in the introduction of fiber optic sensing technologies in medical applications. With its line of fiber optic pressure transducers, flagship product of the company on the medical market, FISO has built a strong reputation in laboratories and medical research centers with the versatility of the solutions it can offer. In addition, the automation level reached in the assembly process allowed FISO to reach the status of world leader as the OEM supplier of fiber optic pressure sensors. 

The FISO-LS Preclinical Pressure Measurement System, exclusively from Harvard Apparatus, represents a new era in micro-catheter pressure measurements. These are the first miniature sensors that can be mass-produced, significantly reducing lead time in getting them into the lab as well as lowering the out-of-pocket costs to the researcher. Because they are fiber optic, they are unaffected by high RF or EM environments. The small sizes - 0.9 and 2 French - mean that they are useful in virtually any application. 

Fiber optic pressure sensors can be used in a wide variety of applications such as urology, cardiovascular physiology, gastroenterology, neuroscience, respiratory phsyiology, ocular physiology and more. Additionally, MRI compatible fiber optic sensors are available when pressures need to be measured in the magnet, for example when triggering the MRI during specific phases of the cardiac cycle.

Passive avoidance is fear-motivated tests classically used to assess short-term or long-term memory on small laboratory animals (rat, mice).

The non-Invasive Blood Pressure (NIBP) test aims to evaluate systemic blood pressure and cardiovascular parameters in rodents without any invasive catheterization.

Smart 3.0, the latest release of Panlab SMART video tracking system features the most flexible and easy-to-learn software for the automated evaluation of behavior in the widest range of pre-clinical and neuroscience applications.

SMART provides data relevant to problems in basic and clinical psychopharmacology. Applications include phenotype characterization (differences between strains, effect of a genetic modification, etc.) and studying the behavioral effects of pharmacologic substances.

Utilizing our advanced image analysis, SMART 3.0 allows the recording of activity, trajectories, events, social interactions, and global activity. SMART 3.0 provides users the versatility of a modular system with the capabilities of a broadband package.

SMART 3.0 was developed with the daily experimental process in mind - easy-to-use interface, highly flexible structure fitting the most applications and budgets. Advanced features ensure reliable data and increased productivity, saving valuable time and resources.

SMART 3.0 emphasizes flexibility, productivity and simplicity - just add your desired settings, SMART 3.0 will do the rest.

Provided data

• Summary tables directly exportable to Excel and providing calculation for each user-defined zones and/or time intervals.
• Wide variety of standard calculations related to tracking: time/distance/entries in zones, average speed... - Advanced calculations also available: alternation triplet, Whishaw’s error, mean directionality, parallel index, turning tendency, rotations ,rearings...
• Zone transition, global activity and events list reporting the time evolution of specific calculations and distribution of their occurrence.
• Track coordinates reports (X,Y,Z)
• Group evolution graphs and Track image exportation

Last available release

Related products

• Open-field box (P)
• Laberinto en cruz elevado (P)
• Elevated zero maze (P)
• Dark light box (P)
• Water Maze (P)
• Radial Maze (P)
• Barnes maze (P)
• T maze (P)
• Y maze (P)
• Place Preference Box - Black & White (P)
• Place Preference Box - Spatial (P)
• Forced swimming test cylinders (P)
• Social box (P)

Forced exercise using a treadmill in rodents is a useful tool with a great value in the study of functional capacity and is a validated standard model for investigations in the field of human metabolism.