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GRIP STRENGTH METER

for evaluation of muscular strength in rodents

Description
Key features
Specs
How to order
Publications

Description

The grip strength meter allows the study of neuromuscular functions in rodents by determining the maximum force displayed by an animal. This test is included in the Functional Observational Battery (FOB) to screen for neurobehavioral toxicity. In this context, changes in grip strength are interpreted as evidence of motor neurotoxicity.

Basically, the grip strength meter is positioned horizontally and the subjects are held by the tail and lowered towards the apparatus. The animals are allowed to grasp the metal grid or triangular pull bar and are then pulled backwards in the horizontal plane. The force applied to the grid or to the bar just before it loses grip is recorded as the peak tension. This force can be measured in grams, Newtons or Ibs.

The grip test includes one accessory by default (bar for rat, grid for rat, bar for mouse or grid for mouse). A different part number is available depending of the included accessory chosen by the customer. The other available accessories can still be added if needed.

Data output is carried out through RS232, printer, or chart recorder. Depending on the grid type used, grip strength can be measured from the front or hind paws.

The SEDACOM 2.0 or BIO-CIS software provides an easy and convenient way to visualize and export the data on a computer for further analysis.

 

Specs

Sensor Capacity 0-2 kG (25N) or 50N (other capacities under request)
Sampling speed 1000 Hz
Measurement Range 0 to 2000 grams
Resolution 1 gram
Accuracy 0.2 % of full scale
Material Composition Stainless steel (Grid)
Power Supply Accumulator 4 hours and/or 220V or 240V. Other powersupply on request
Dimensions of single system 400 (W) x 180 (D) x 200 (H) mm

Publications

  • Son JS et al. (2017) Effects of exercise-induced apelin levels on skeletal muscle and their capillarization in type 2 diabetic rats. Muscle Nerve. 2017 Dec;56(6):1155-1163. (rat, South Korea)
  • Haulcomb MM et al. (2017) Locomotor analysis identifies early compensatory changes during disease progression and subgroup classification in a mouse model of amyotrophic lateral sclerosis. Neural Regen Res. 2017 Oct;12(10):1664-1679. (mouse, US)
  • Grønhøj MH et al. (2017) Beneficial potential of intravenously administered IL-6 in improving outcome after murine experimental stroke. Brain Behav Immun. 2017 Oct;65:296-311. (mouse, Denmark)
  • Meyer A et la. (2017) IFN-β-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis. Acta Neuropathol. 2017 Oct;134(4):655-666. (mouse, France)
  • Pytka K et al. (2017) HBK-14 and HBK-15, triple 5-HT1A, 5-HT7 and 5-HT3 antagonists with potent antidepressant- and anxiolytic-like properties, increase seizure threshold in various seizure tests in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt B):378-385. (mouse, Poland)
  • El Oussini H et al. (2017) Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis. Ann Neurol. 2017 Sep;82(3):444-456. (mouse, France, Germany)
    Kim HJ et al. (2017) Resistance training increases fibroblast growth factor-21 and irisin levels in the skeletal muscle of Zucker diabetic fatty rats. J Exerc Nutrition Biochem. 2017 Sep 30;21(3):50-54. (rat, South Korea)
  • Benoit B et al. (2017) Fibroblast growth factor 19 regulates skeletal muscle mass and ameliorates muscle wasting in mice. Nat Med. 2017 Aug;23(8):990-996. (mouse, Norway, France)
  • Chanet A et al. (2017) Vitamin D supplementation restores the blunted muscle protein synthesis response in deficient old rats through an impact on ectopic fat deposition. J Nutr Biochem. 2017 Aug;46:30-38. (rat, France)
  • Adongo DW et al. (2017) Anticonvulsant activity of Pseudospondias microcarpa (A. Rich) Engl. hydroethanolic leaf extract in mice: The role of excitatory/inhibitory neurotransmission and nitric oxide pathway. J Ethnopharmacol. 2017 Jul 12;206:78-91. (mouse, Ghana)
  • Mobley CB et al. (2017) Aging in Rats Differentially Affects Markers of Transcriptional and Translational Capacity in Soleus and Plantaris Muscle. Front Physiol. 2017 Jul 20;8:518. (rat, US)
  • Socała K et al. (2017) Increased seizure susceptibility and other toxicity symptoms following acute sulforaphane treatment in mice. Toxicol Appl Pharmacol. 2017 Jul 1;326:43-53. (mouse, Poland)
  • Chacon-Cabrera A et al. (2017) Short- and Long-Term Hindlimb Immobilization and Reloading: Profile of Epigenetic Events in Gastrocnemius. J Cell Physiol. 2017 Jun;232(6):1415-1427. (mouse, Spain)
  • Scekic-Zahirovic J et al. (2017) Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. Acta Neuropathol. 2017 Jun;133(6):887-906. (mouse, Germany, US)
  • Mothe-Satney I et al. (2017) Peroxisome Proliferator Activated Receptor Beta (PPARβ) activity increases the immune response and shortens the early phases of skeletal muscle regeneration. Biochimie. 2017 May;136:33-41. (mouse, France)
  • Marmonti E et al. (2017) A Rat Immobilization Model Based on Cage Volume Reduction: A Physiological Model for Bed Rest? Front Physiol. 2017 Mar 29;8:184. (rat, Spain)
  • Van Dijk M et al. (2017) Sarcopenia in older mice is characterized by a decreased anabolic response to a protein meal. Arch Gerontol Geriatr. 2017 Mar - Apr;69:134-143. (mouse, The Netherland, France)
  • Tutka P et al.(2017) Cytisine inhibits the protective activity of various classical and novel antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice. Psychopharmacology (Berl). 2017 Jan;234(2):281-291. (Mouse, Poland)
  • Lafoux A et al. (2016) Soluble Milk Protein Supplementation with Moderate Physical Activity Improves Locomotion Function in Aging Rats. PLoS One. 2016 Dec 14;11(12):e0167707. (rat, France)
  • Kravic B et al. (2016) LAP proteins are localized at the post-synaptic membrane of neuromuscular junctions and appear to modulate synaptic morphology and transmission. J Neurochem. 2016 Nov;139(3):381-395. (mouse, Germany, France)
  • Clausen BH et al. (2016) Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling. Sci Rep. 2016 Jul 7;6:29291. (mouse, Denmark, USA)
  • Manso C et al. (2016) Contactin-1 IgG4 antibodies cause paranode dismantling and conduction defects. Brain. 2016 Jun;139(Pt 6):1700-12. (rat, France, Spain)
  • Son JS et al. (2016) Effect of resistance ladder training on sparc expression in skeletal muscle of hindlimb immobilized rats. Muscle Nerve. 2016 Jun;53(6):951-7. (rat, South Korea)
  • Park HY et al. (2016) Gadd45β ameliorates L-DOPA-induced dyskinesia in a Parkinson's disease mouse model. Neurobiol Dis. 2016 May;89:169-79. (mouse, South Korea)
  • Chali F et al. (2016) Long-term exercise-specific neuroprotection in spinal muscular atrophy-like mice. J Physiol. 2016 Apr 1;594(7):1931-52. (mouse, France)
  • Reimann A et al. (2016) Combined administration of the GPVI-Fc fusion protein Revacept with low-dose thrombolysis in the treatment of stroke. Heart Int. 2016 Apr 25;11(1):e10-e16. (mouse, Germany)
  • Toledo M et al. (2016) Complete reversal of muscle wasting in experimental cancer cachexia: Additive effects of activin type II receptor inhibition and β-2 agonist. Int J Cancer. 2016 Apr 15;138(8):2021-9. (mouse, Spain)
  • Socała K et al. (2016) SB 334867, a selective orexin receptor type 1 antagonist, elevates seizure threshold in mice. Life Sci. 2016 Apr 1;150:81-8. (mouse, Poland)
  • Weiss JM et al. (2016) Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis. Oncotarget. 2016 Feb 16;7(7):7550-62. (mouse, France)
  • And much more citations available...

 

How to order

CONTROL UNIT & SENSOR PACKAGES

BSBIOGS3BR

76-1065

Grip test package (25N), with one Bar for Rat

BSBIOGS3BS

76-1066

Grip test package (25N), with one Bar for Mouse

BSBIOGS3GR

76-1067

Grip test package (25N), with one Grid for Rat

BSBIOGS3GS

76-1068

Grip test package (25N), with one Grid for Mouse

  BAR & GRID ACCESSORIES

BSBIOGRIPBR

76-0479

Additional bar for rats - Front or hind Paws

BSBIOGRIPBS

76-0480

Additional bar for mice - Front or hind Paws

BSBIOGRIPGR

76-0481

Additional grid for rats - Front paws or four paws

BSBIOGRIPGS

76-0482

Additional grid for mice - Front paws or four paws

 DATA TRANSFER

SEDACOM V2.0

76-0406

SeDaCom V2.0 software for data transfer to a computer (needs the 76-1014 cable)

BSELECENTORRS232

76-1014

RS232/USB Cable for SEDACOM software

BSBIOCIS

76-0741

BIO-CIS Software, incl. RS232/USB cable

OTHER OPTIONS

BSETBIOGT

76-1008

GRIP TEST Calibration Certificate

 

How to order

Please contact our local delegates or contact us directly for receiving a quote.

 

Key features

  • Easy to use and large back-lighted screen
  • Stand-alone system, no need of computer
  • Fit to Rats and Mice while needing only changing grip accessories
  • Multi-units display : Kgs, grams, LBs Newton...

 

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