Gold Standard for Neuromuscular Studies

We provide he scientifically validated gold standard rodent grip strength system, designed to reduce publication risk, preserve continuity with historical datasets, and capture true peak force events in mice and rats.

Our users are not just buying a grip meter—they are buying continuity with two decades of published rodent strength data for neurotoxicity FOB workflows, CNS disease models and mouse phenotyping pipelines.

The GS4 Grip Strength Test allows the study of neuromuscular functions by determining the maximal peak force developed by a rodent (rat or mouse) when the operator tries to pull it out of a specially designed grid or bar, which are available for both fore and hind limbs. With over 2,000 of peer-reviewed scientific publications, the GS4 grip test is used by hundreds of labs worldwide, including major mouse phenotyping centers.

With over 2,000 of peer-reviewed scientific publications, our family of grip tests is used by hundreds of labs worldwide, including major mouse phenotyping centers.

• Inter-study comparability, reproducibility confidence
• Method continuity, lower reviewer friction

The GS4 Grip test is also ideal for CRO and pharma teams requiring harmonized SOP execution, lower operator variability, and continuity across long-term preclinical programs.

IMPORTANT: The GS4 Grip test captures the real biological peak, not an averaged/filtered approximation.

For mouse disease models (such as ALS, DMD, Parkinson’s, denervation, aging sarcopenia…) force peaks are often very brief transient spikes. In that context, for translational neurodegeneration work, raw peak capture over is always more accurate than the post hoc filtering used by other low-cost grip test systems. At the end, a cheaper device that misses transient peaks is more expensive than a premium device that captures publishable truth.

This is why the GS4 grip strength meter with its 1000 Hz high sampling rate acquisition is the best option of the market for the preservation of raw peak validity.

A high sampling acquisition rate:

• captures short peak force events better
• reduces underestimation of true maximum force
• is especially useful in weak mice, ALS, DMD, Parkinsonian, or nerve injury models

Accessories specially designed to reduce data variability.

The GS4 Grip Strength Test apparatus is the third version based on Bioseb's methodology. The first version was developed in 1999, and Bioseb's Grip Strength Test now counts hundreds of users around the world who provided continuous feedback about how to improve the design of the bar/grid accessories in order to decrease variability and increase the reproducibility of the studies. In this context, every detail can make a huge difference.

The GS4 grip test works with a wide variety of accessories for rodents: Grids for 4 paws, T bars for front or hind paws and L bars for lateralized tests.

BIOCIS2 software – Get the best of your grip strength test

The BIO-CIS2 Software allows you to get the best of your Grip Strength Test by monitoring in real time your experiments or importing your recorded data from your device to your computer.

A NEW version of the BIOCIS software now available for increasing the repeatability of nociceptive tests: by recording the reflex respond the software help the operator to improve his skills with the instrument, as well as to invalidate off-limit results. A brand-new function also allows the importation of all data from a wide range of instruments directly into Excel for further analysis!

• Works with Grip Test, Rodent Pincher, Electronic Von Frey, Smalgo, and Static Weight Bearing Test
• Real-time curve tracing of the applied force
• Peak force determination (as displayed on the instrument)
• Allows the definition of a theoretical ramp (force/time unit) with up-down limits to be followed and displayed during the measurement
• Curves of a group of measures can be reloaded and displayed simultaneously for a graphical overview
• Export results to an Excel file or txt format: peak values or full measurement curves
• Sequential import of measurement data by pressing the pedal, thus sending data to the spreadsheet
• Bulk import to send all stored data into Excel
• Excel spreadsheet can be customized by teaching Bio-CIS2 where to write data in your files