Grip strength test

Description
Related Panlab Integrated Solutions

Description

The purpose of this test is to evaluate the limb motor or muscular functions in rodents. 

The grip strength meter test allows the study of neuromuscular functions in rodents by determining the maximum force displayed by an animal. This test is included in the Functional Observational Battery (FOB) to screen for neurobehavioral toxicity. In this context, changes in grip strength are interpreted as evidence of motor neurotoxicity.

Basically, the grip strength meter is positioned horizontally and the subjects are held by the tail and lowered towards the apparatus. The animals are allowed to grasp the metal grid or triangular pull bar and are then pulled backwards in the horizontal plane. The force applied to the grid or to the bar just before it loses grip is recorded as the peak tension.

The major challenge of this test is the great inter-individual variation of the data between the subjects so a special care has to be done about animal habituation/ handling and experimenter training. 

The grip strength test represents a complementary test to the rotarod test.

 

Related Panlab Integrated Solutions


GRIP STRENGTH METER (Bioseb) – complete system for rat & mice

  • 1 x Grip strength test package with one grip/bar system (can be the 761065/BSBIOGS3BR including 1 bar for rat  for instance)
  • 1 x 76-0479/BSBIOGRIPBS - additional bar for mouse
  • 1 x 76-0480/BSBIOGRIPGR - additional grid for rat
  • 1 x 76-0481/BSBIOGRIPGS - additional grid for mouse
  • 1 x 76-0482 SEDACOM V2.0 software (option)
  • 1 x 76-0406 BSELECENTORRS232 adapter (option)

The data of the experiment are shown on the display of the grip strength control unit. 

The 76-0482 SEDACOM/76-0406 BSELECENTORRS232 option is recommended for an easy exportation of the data to a computer and Excel. 

 


GRIP STRENGTH METER (Bioseb) – complete system for rat

  • 1 x Grip strength test package with one grip/bar system (can be the 761065/BSBIOGS3BR incuding 1 bar for rat  for instance)
  • 1 x 76-0480/BSBIOGRIPGR - additional grid for rat
  • 1 x 76-0482 SEDACOM V2.0 software (option)
  • 1 x 76-0406 BSELECENTORRS232 adapter (option)

The data of the experiment are shown on the display of the grip strength control unit. 

The 76-0482 SEDACOM/76-0406 BSELECENTORRS232 option is recommended for an easy exportation of the data to a computer and Excel. 

 


GRIP STRENGTH METER (Bioseb) – complete system for mice

  • 1 x Grip strength test package with one grip/bar system (can be the 76-1066/BSBIOGRIPBS  including 1 bar for mouse)
  • 1 x 76-0481/BSBIOGRIPGS - additional grid for mouse
  • 1 x 76-0482 SEDACOM V2.0 software (option)
  • 1 x 76-0406 BSELECENTORRS232 adapter (option)

The data of the experiment are shown on the display of the grip strength control unit. 

The 76-0482 SEDACOM/ 76-0406 BSELECENTORRS232option is recommended for an easy exportation of the data to a computer and further exportation to Excel. 

 


 

 

Reasons for choosing this test

  • Easy and rapid test
  • Sensitive for both rats and mice

Reasons for not choosing this test

  • High variability in the response
  • Habituation to the response inducing a loss of motivation when measurements are performed at short interval
  • Influenced by user handling (need training)
 
 
 
 
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