ROTA ROD

for Motor Coordination, Endurance, and Fatigue Resistance Studies

Description
Key features
Specs
How to order
Publications

Description

Our Rota Rod (or rotarod) provides an easy way to test the effects of drugs, brain damage, or diseases on motor coordination or fatigue resistance in rodents.

The animal is placed on the rotating lane of the Rota Rod and the timer is started. When the animal drops safely into its own lane, the time latency to fall (minutes and seconds) and rotation speed are automatically recorded. A removable upper separator for rat models is included to prevent interference between animals running in adjacent lanes.

The Rota Rod is controlled by an advanced microprocessor which provides precise timing control and ultra-accurate speed regulation. Rotation can be electronically set at a constant speed (4-40 rpm). Alternatively, acceleration rate may be selected at a defined time (30 sec to 10 min, 1 sec increments). Acquired data is saved in table form by lanes/trials.

Now even easier to use! The new touchscreen graphic user interface allows clear visualization of timing and speed for each lane. Change modes, adjust speed, and create protocols right from the main screen for greater flexibility with maximum functionality and usability.

 

Parameters measured

  • Animal latency to fall
  • Rotation speed when fall occurs

 

 

Specs

Model

LE8205

LE8305

LE8505

LE8355

Subject weight range

up to 60g

up to 300/400g

up to 60g - mouse drum; up to 350/400g - rat drum

>350/400g up to 500/600g

Base Unit Dimensions mm (inch) (W x D x H)

362 x 240 x 375 (14.25 x 9.45 x 14.75)

362 x 240 x 375 (14.25 x 9.45 x 14.75)

362 x 240 x 375 (14.25 x 9.45 x 14.75)

362 x 245 x 624 (14.25 x 9.65 x 24.57)

Total Height mm (inch)

400 (15.75)

400 (15.75)

400 (15.75)

649 (25.55)

Fall Height cm

20

21.5

20 (mouse drum); 21.5 (rat drum)

47

Lane Width mm (inch)

50 (2)

75 (3)

50 (2) - mouse drum; 75 (3) - rat drum

153 (6)

Drum Diameter mm (inch)

250 (9.8)

250 (9.8)

250 (9.8)

250 (9.8)

Rod Diameter mm (inch)

30 (1)

60 (2)

30 (1) - mouse drum; 60 (2) - rat drum

80 (3)

Extra Hood Height mm (inch)

NA

130 (5)

130 (5)

130 (5)

Constant Speeds

4-40 RPM

4-40 RPM

4-40 RPM

4-40 RPM

Acceleration Rate

30 seconds to 10 minutes with 1 sec increments

30 seconds to 10 minutes with 1 sec increments

30 seconds to 10 minutes with 1 sec increments

30 seconds to 10 minutes with 1 sec increments

Material Composition

Methacrylate, arnite (lanes)

Methacrylate, arnite (lanes)

Methacrylate, arnite (lanes)

Methacrylate, arnite (lanes)

Publications

ROTAROD

 

  • Graber TG et al. (2018) Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexia. Exp Gerontol. 2018 Jun;106:88-100. (mouse, USA)
  • Díaz D at al. (2018) Bone marrow transplantation improves motor activity in a mouse model of ataxia. J Tissue Eng Regen Med. 2018 Apr;12(4):e1950-e1961. (mouse, Spain)
  • Kossatz E et al. (2018) Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice. Front Pharmacol. 2018 Apr 19;9:376. (mouse, Spain)
  • Leitão RA et al. (2018) Aquaporin-4 as a New Target against Methamphetamine-Induced Brain Alterations: Focus on the Neurogliovascular Unit and Motivational Behavior. Mol Neurobiol. 2018 Mar;55(3):2056-2069. (mouse, Portugal)
  • Niemir N et al. (2018) Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice. Hum Mol Genet. 2018 Mar 15;27(6):954-968. (mouse, France)
  • Sarubbo F et al. (2018) Chronic Silymarin, Quercetin and Naringenin Treatments Increase Monoamines Synthesis and Hippocampal Sirt1 Levels Improving Cognition in Aged Rats. J Neuroimmune Pharmacol. 2018 Mar;13(1):24-38. (rat, Spain)
  • Xiong LL et al. (2018) Neural Stem Cell Transplantation Promotes Functional Recovery from Traumatic Brain Injury via Brain Derived Neurotrophic Factor-Mediated Neuroplasticity. Mol Neurobiol. 2018 Mar;55(3):2696-2711. (rat, China)
  • Pak ME et al. (2018) Combined therapy involving electroacupuncture and treadmill exercise attenuates demyelination in the corpus callosum by stimulating oligodendrogenesis in a rat model of neonatal hypoxia-ischemia. Exp Neurol. 2018 Feb;300:222-231. (rat, Republic of Korea)
  • Peng S et al. (2018) Achyranthes bidentata polypeptide protects dopaminergic neurons from apoptosis in Parkinson's disease models both in vitro and in vivo. Br J Pharmacol. 2018 Feb;175(4):631-643. (mouse, China)
  • Wang YY et al. (2018) Impaired glutamatergic projection from the motor cortex to the subthalamic nucleus in 6-hydroxydopamine-lesioned hemi-parkinsonian rats. Exp Neurol. 2018 Feb;300:135-148. (rat, China)
  • Gil CH et al. (2018) Aripiprazole exerts a neuroprotective effect in mouse focal cerebral ischemia. Exp Ther Med. 2018 Jan;15(1):745-750. (mouse, Republic of Korea)

 

Contact us for a more complete list of publications.

 

How to order

ROTAROD MODELS

Order #

Model

Product

76-0770

LE8205

Accelerating Rota Rod with Touchscreen, 5 Mice

76-0771

LE8305

Accelerating Rota Rod with Touchscreen, 4 Rats

76-0772

LE8505

Accelerating Rota Rod with Touchscreen, 4 Rats or 4 Mice

76-0773

LE8355

Accelerating Rota Rod with Touchscreen, 2 Large Rats

DATA OUTPUT OPTIONS

Order #

Model

Product

76-0406

SEDACOM

Sedacom V2.0 Software

SPARE PARTS 

Order #

Model

Product

76-0373

LE8580

4 Rat Drum for LE8505

76-0371

LE8550

4 Mice Drum for LE8505

 

How to order

Please contact our local delegates or contact us directly for receiving a quote.

 

Key features

  • NEW Touchscreen User Interface
  • Combined Rota Rod for mice and rats available
  • Mechanical detection of fall
  • Individual lane timers
  • Constant speed and fixed acceleration rate modes

 

Rel. products

Related tests

Rotarod test

 
 
 
 
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