For active and passive avoidance

Key features
How to order


SHUTAVOID software is an implemented version of the Panlab SHUTTLE-8 software offering a user-friendly interface to conduct active and passive avoidance procedures in an automated manner. 

The Software SHUTAVOID controls independently up to 8 Shuttle Boxes or Passive Cages. The software detects how many cages are physically present and activates the corresponding windows. The system includes a test mode to enables immediate and reliable checking of the functioning of all the elements of the experimental chamber. 

The program controls the presentation of visual and acoustic stimuli and shock duration, at the same time that it records the position of the experimental animal in each compartment of the experimental cage, deciding about stimuli presentation accordingly. 

Unlimited number of schedules can be defined and used either by common or different experimental cages. The protocol editor allows the configuration of all the basic parameters necessary to set an active and passive avoidance experiment: habituation period, duration of the inter-trial interval (fixed or randomized), activation and duration of the conditioned stimulus (light, sound or both), activation, latency and duration of the unconditioned stimulus (electrical shock), latency for considering the response as “null”, door status (open/closed), number of trials, cut-off time for response etc… 

The chambers can be defined as Independent (for classical active avoidance procedures), Master or Slaves (for yoked procedures in which the paired-yoked animals receive the same number and temporal pattern of stimuli as their master mates, but only the master animal controls the outcome of the response). 

The program runs automatically when the animal is detected in the cage (independently for each cage). During the acquisition of data, information about the protocol state, animal position and current data can be visualized for each cage on the corresponding control window. 

Data related to each of the observed animal responses are stored into result files that pick up the information acquired during the working session. The data files can be open and re-analyzed to generate ASCII-coded reports in which the information is summarized for each trial or groups of trials (user-defined). 




Computer requirements 2,2 GHz processor or higher (Celeron processor not supported), 2 Gb of RAM
Graphic Card Requirements 256 colours palette graphics card for 1024x768 pixels, 32-bit true colour RGB display.
Communication ports 1 free USB for the protection key; 1 free RS232 serial port for boxes connection (a USB-Serial adapter included in the software pack can be used when a RS-232 serial port is not available)
System requirements Microsoft® Windows® 7 - 32/64 bits; Windows® 8 - 32/64 bits, Windows® 10 - 32/64 bits


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  • Segura-Torres P et al. (2010) Intracranial self-stimulation recovers learning and memory capacity in basolateral amygdala-damaged rats. Neurobiology of Learning and Memory, Volume 93, Issue 1, January 2010, Pages 117–126. (active avoidance, rat, Spain)
  • García-Capdevila S et al. (2009) Effects of long-term voluntary exercise on learning and memory processes: dependency of the task and level of exercise. Behavioural Brain Research, Volume 202, Issue 2, 14 September 2009, Pages 162–170. (active avoidance, Spain)
  • Dagnino-Subiabre A et al. (2009) Chronic stress induces dendritic atrophy in the rat medial geniculate nucleus: Effects on auditory conditioning Behavioural Brain Research203(1):88-96 (rat, Chile, USA)
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  • Lopez-Aumatell R et al. (2008) Fearfulness in a large N/Nih genetically heterogeneous rat stock: differential profiles of timidity and defensive flight in males and females. Behavioural Brain Research, Volume 188, Issue 1, 17 March 2008, Pages 41–55. (active avoidance, rat, Spain, UK)
  • Martin-Garcia et al (2008) Neonatal finasteride induces anxiogenic-like profile and deteriorates passive avoidance in adulthood after intrahippocampal neurosteroid administration. Neuroscience. 154(4):1497-1505 (rat, Spain)
  • Mendez et al. (2008) Associative learning deficit in two experimental models of hepatic encephalopathy. Behavioural Brain Research, Volume 198, Issue 2, 17 March 2009, Pages 346-351. (rat, Spain)
  • Rueda N et al. (2008) Effects of chronic administration of SGS-111 during adulthood and during the pre- and post-natal periods on the cognitive deficits of Ts65Dn mice, a model of Down syndrome. Behavioural Brain Research, Volume 188, Issue 2, 9 April 2008, Pages 355-367 (mouse, Spain)
  • Ruiz-Medina J et al (2008) Intracranial self-stimulation improves memory consolidation in rats with little training. Neurobiol. Learn. Mem. 89(4):574-581 (rat, Spain)
  • Trigo JM et al (2008) MDMA modifies active avoidance learning and recall in mice. Psychopharmacol. 197:391-400 (mouse, Spain)
  • Andero R et al. (2007) Electrical stimulation of the pedunculopontine tegmental nucleus in freely moving awake rats: Time- and site-specific effects on two-way active avoidance conditioning. Neurobiol. Learn. Mem. 87(4):510-521 (rat, Spain)
  • Bura SA et al. (2007) Genetic and pharmacological approaches to evaluate the interaction between the cannabinoid and cholinergic systems in cognitive processes. Br J Pharmacol. 2007 March; 150(6): 758–765. (mice, Spain, Belgium)
  • Quiroz-Padilla MF et al. (2007) Effects of parafascicular excitotoxic lesions on two-way active avoidance and odor-discrimination. Neurobiol. Learn. Mem. (active avoidance, rat, Spain)
  • Lopez-Aumatell R et al. (2007) Fearfulness in a large N/Nih genetically heterogeneous rat stock: Differential profiles of timidity and defensive flight in males and females. Behav. Brain Res. 188(1):41-55 (rat, Spain)
  • Millan M et al. (2007) A preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. III. Actions in models of therapeutic activity and induction of side-effects. J. Pharmacol. Exp. Ther. (active avoidance, rat, France)
  • Soriano-Mas C et al. (2007) Intracranial self-stimulation after memory reactivation: Immediate and late effects. Brain Res. Bull. 74(1-3):51-57 (rat, Spain)
  • Norby T et al. (2006) Posttraining epinephrine treatment reduces the need for extensive training. Physiology & Behavior, Volume 89, Issue 5, 30 December 2006, Pages 718–723. (active avoidance, rat, Spain)
  • Vicente F et al. (2006) Immunization and facilitation produced by predictable and controllable aversive events alternating with different duration unpredictable and uncontrollable aversive events. Int. J. Psychol. 41(5): 385-396. (learned heplessness, rat, spain)
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  • Montero-Pastor A et al. (2004) Effects of electrical stimulation of the nucleus basalis on two-way active avoidance acquisition, retention, and retrieval. Behavioural Brain Research, Volume 154, Issue 1, 23 September 2004, Pages 41–54. (active avoidance, rat, Spain)
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  • Redolar-Ripoll D et al. (2003) Posttraining intracranial self-stimulation ameliorates the detrimental effects of parafascicular thalamic lesions on active avoidance in young and aged rats. Behavioral Neuroscience, Vol 117(2), Apr 2003, 246-256. (active avoidance, rat, Spain)
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  • Morón I et al. (2002) Differential effects of bicuculline and muscimol microinjections into the nucleus basalis magnocellularis in taste and place aversive memory formation. Behav. Brain Res. 134: 425-431. (rat, Spain, Mexico)
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How to order




PC Software to control up to 8 Shuttle Boxes or Passive Avoidance Boxes

How to order

Please contact our local delegates or contact us directly for receiving a quote.


Key features

  • Allows editing protocols for both active and passive avoidance
  • Experimental chambers can be controlled independently
  • A Test mode enables immediate and reliable box checking
  • New configuration panel for Yoked procedures
  • The program runs automatically when the animal is detected in the cage
  • Animal position and current data can be visualized on-line
  • Provides integrated data
  • Re-analyses data in user-defined intervals of time


Rel. products

  • Shuttle box
  • Passive avoidance box

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Passive avoidance test

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