METABOLISM Software

for respiratory metabolism, intake and activity in rodents

Description
Key features
Specs
How to order
Publications

Description

METABOLISM software is the last element of the chain of components of the Panlab OXYLET,FOOD and DRINK and PHYSIOCAGE systems. METABOLISM allows the extraction of the data obtained from these Panlab devices as well as the calculation of important parameters for physiological studies. A combined evaluation of the respiration metabolism, food/drink intake, spontaneous activity and rearing is then rendered possible by the use of this very simple and easy-to-use software.

METABOLISM consists in different modules, activated upon customer request:

  • METAOXY -> for O2/CO2 metabolism studies (Including Treadmill based studies).
  • METAINT -> for Intake studies
  • METAACT -> for activity studies (Including Rearing)

The program gets data in digital form from the Panlab devices. METABOLISM can also import and convert analogical data from the *.txt files generated by Data Acquisition Systems (PowerLab® recommended). 

Gathered data can be processed and re-processed using different time intervals of calculation. The program displays a Data Table which can be saved in Excel format for further analyses.

 

Specs

Computer requirements

3 GHz Processor or higher (CELERON excluded; 4GHz recommended), 2 Gb of RAM,150 MB HD, Graphics 1024x768 pixels and 32-bit true colour.

Software requirements

Windows™ XP (SP2 or higher), Vista 32, Windows 7 or Windows 8 compatible operating system

Publications

  • Casuso Ra et al. (2013) Ergogenic effects of quercetin supplementation in trained rats. J. Int. Society of Sports Nutrition. 10:3-7 (LE8710R, VO2 mx, exhaustion, rat, Spain)
  • Cappelli AP et al. (2013) Taurineinduced insulin signalling improvement of obese malnourished mice is associated with redox balance and protein phosphatases activity modulation. Liver International. In Press. (mouse, Brazil)
  • Cettour-Rose P et al. (2013) Quinine controls body weight gain without affecting food intake in male C57BL6 mice. (mice, Switzerland, Japan).
  • Coutinho GVP et al. (2013) Intrauterine protein restriction combined with early postnatal overfeeding was not associated with adult-onset obesity but produced glucose intolerance by pancreatic dysfunction. Coutinho et al. Nutrition & Metabolism 2013, 10:5. (rat, Brazil)
  • Fortunado G et al. (2013) Recovery of pulmonary structure and exercise capacity by treatment with granulocyte-colony stimulating factor (G-CSF) in a mouse model of emphysema. Pulmonary Pharmacology & Therapeutics. In press (mice, treadmill, Brazil).
  • Hyun-Ju K et al. (2013) Metformin decreases meal size and number and increases c-Fos expression in the nucleus tractus solitarius of obese mice. Physiology & Behavior. 110-111:213-220. (Obese mice, Republic of Korea.)
  • Ikonomov OC et al. (2013) Muscle-specific Pikfyve gene disruption causes glucose intolerance, insulin resistance, adiposity and hyperinsulinemia but not muscle fiber-type switching. Am J Physiol Endocrinol Metab. 2013 Jul 1;305(1):E119-31. (mouse, USA)
  • Kim HJ et al. (2013) Central administration of metformin into the third ventricle of C57BL/6 mice decreases meal size and number and activates hypothalamic S6 kinase. American Journal of Physiology - Vol. 305no. R499-R505. (mouse, Korea)
  • Kim HJ et al. (2013) Metformin decreases meal size and number and increases c-Fos expression in the nucleus tractus solitarius of obese mice. Physiology & Behavior, Volumes 110–111. (mouse, Korea)
  • Kim YJ et al. (2013) Longterm supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in highfat fed mice. Molecular Nutrition & Food Research, Volume 57, Issue 11, pages 1988–1998 (mouse, Korea)
  • Larocca TF et al. (2013) Transplantation of adipose tissue mesenchymal stem cells in experimental chronic chagasic cardiopathy. Arq. Bras. Cardiol. vol.100 no.5 (mouse, Brazil)
  • Ahn J. et al. (2012) Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice. Food and Chemical Toxicology. 51: 439-445 (obesity, mice, Republic of Korea)
  • Attané C et al. (2012) Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice. Diabetes. 61(2):310-320. (diabetes, obesity, mice, France)
  • Benani A et al. (2012) Food Intake Adaptation to Dietary Fat Involves PSA-Dependent Rewiring of the Arcuate Melanocortin System in Mice. The Journal of Neuroscience. 32(35):11970-11979. (obesity, mice, France)
  • Burgos-Ramos E et al. (2012) Differential Insulin Receptor Substrate-1 (IRS1)-Related Modulation of Neuropeptide Y and Proopiomelanocortin Expression in Nondiabetic and Diabetic IRS2−/− Mice. 153(3):1129-1140. (diabetes, mice, Spain)
  • Dhanesha N et al (2012) Inhibition of 11β-hydroxysteroid dehydrogenase 1 by carbenoxolone affects glucose homeostasis and obesity in db/db mice. Clin. Exp. Pharmacol. Physiol. 39(1):69-77. (glucose homeostasis, mice, India)
  • Elias I et al. (2012) Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance. Diabetes. 61(7):1801-1813. (Obesity, mice, Spain)
  • González-Rodríguez A et al. (2012) Essential role of protein tyrosine phosphatase 1B in obesity-induced inflammation and peripheral insulin resistance during aging. Aging Cell 11(2):284-296. (obesity, mice, Spain,USA)
  • Maris M et al. (2012) Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance. Diabetologia. 55(4):1167-1178. (diabetes, obesity, mice, Belgium).
  • Stucchi P et al (2012) Circadian Feeding Drive of Metabolic Activity in Adipose Tissue and not Hyperphagia Triggers Overweight in Mice: Is There a Role of the Pentose-Phosphate Pathway? Endocrinology. Diabetes. 153(2):690-699. (obesity, mice, Spain)
  • Razolli DS et al. (2012) Hypothalamic action of glutamate leads to body mass reduction through a mechanism partially dependent on JAK2. Journal of Cellular Biochemistry, Volume 113, Issue 4, pages 1182–1189. (rat, Brazil)
  • Vidal D et al. (2012) Alterations in pulmonary structure by elastase administration in a model of emphysema in mice is associated with functional disturbances. Revista Portuguesa de Pneumologia (English Edition), Volume 18, Issue 3, May–June 2012, Pages 128–136. (mouse, Brazil)
  • Vinolo MAR et al. (2012) Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice. American Journal of Physiology Vol.303 no.E272-E282. (mouse, Brazil)
  • Bojados M et al. (2011) Exposure to hypergravity during specific developmental periods differentially affects metabolism and vestibular reactions in adult C57BL/6j mice. European Journal of Neuroscience, Volume 34, Issue 12, pages 2024–2034. (mouse, France)
  • Kim CS et al. (2011) Deficiency for Costimulatory Receptor 4-1BB Protects Against Obesity-Induced Inflammation and Metabolic Disorders. Diabetes, 60(12):3159-3168. (obesity, mice, South Korea)
  • Luque et al. (2011) Metabolic impact of Adult-Onset, isolated, Growth Hormone Deficiency (AOiGHD) due to destruction of pituitary somatropes. PloS ONE, 6(1):e15767 (Oxylet - Physiocage, calorimetry, activity, mouse, USA)
  • Marissal-Arvy N et al. (2011) Functional variability in corticosteroid receptors is a major component of strain differences in fat deposition and metabolic consequences of enriched diets in rat. Metabolism, 60(5):706-719. (obesity, rat, France)
  • Mulvihill EE et al. (2011) Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance. Diabetes, 60(5):1446-1457. (dyslipidemia, mice, Canada)
  • Penna F et al. (2011) Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise. J. Cachexia Sarcopenia Muscle. 2(2):95-104.  (treadmill, VO2max, mice, Italy)
  • Pratte M et al. (2011) Progressive motor and respiratory metabolism deficits in post-weaning Mecp2-null male mice. Behavioral Brain Research. 216(1):313-320. (respiratory metabolism, mice, France)
  • Prawitt J et al. (2011) Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity. 60(7):1861-1871. (obesity, mice, France)
  • Crescenzo R et al. (2010) Hepatic mitochondrial energetics during catch-up fat after caloric restriction. Metabolism. (energy balance, 24h measurement, 4 cages, rats, Italy).
  • Hur YN et al. (2010) High fat diet altered the mechanism of energy homeostasis induced by nicotine and withdrawal in C57BL/6 mice. Molecules and Cells, Volume 30, Issue 3, pp 219-226. (mouse, Korea)
  • Lomba A et al. (2010) Obesity induced by a pair-fed high fat sucrose diet: methylation and expression pattern of genes related to energy homeostasis. Lipids in Health and Disease 9:60 (Oxylet – Physiocage, rats, Spain)
  • Lomba A et al. (2010) Weight gain induced by an isocaloric pair-fed high fat diet: a nutriepigenetic study on FASN and NDUFB6 gene promoters. Molecular Genetics and Metabolism, Volume 101, Issues 2–3, Pages 273–278. (rat, Spain)
  • Pospisilik JA, et al. (2010) Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell. 140(1):148-60. (calorimetry, mouse, Austria)
  • Pratt M et al. (2010) Progressive motor and respiratory metabolism deficits in post-weaningMecp2-null male mice. Behav. Brain Res. 216(1):313-320. (Treadmill with calorimetry VOmax, mouse, France).
  • Stenger C et al. (2010) Up-regulation of hepatic lipolysis stimulated lipoprotein receptor by leptin: a potential lever for controlling lipid clearance during the postprandial phase. FASEB J. 24(11): 4218-4228. (Oxylet, mouse, France).
  • Wallmann J et al. (2010) Mimotope vaccination for therapy of allergic asthma: antiinflammatory effects in a mouse model. Clinical & Experimental Allergy, Volume 40, Issue 4, pages 650–658. (mouse, Austria)
  • Dominguez JF et al. (2009) Novel Indirect Calorimetry Technology to Analyze Metabolism in Individual Neonatal Rodent Pups. PLoS One. 4(8):e6790. (neonate rat, USA)
  • Macambira SG et al. (2009) Granulocyte colony-stimulating factor treatment in chronic Chagas disease: preservation and improvement of cardiac structure and function. FASEB J. 23(11):3843-50. (Treadmill with calorimetry, mouse, Brazil)
  • Lebrun P et al. (2009) Constitutive expression of suppressor of cytokine signalling-3 in skeletal muscle leads to reduced mobility and overweight in mice. Diabetologia, 52(10):2201-2212. (mouse, France)
  • Mulvihill EE et al. (2009) Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor–Null Mice With Diet-Induced Insulin Resistance. Diabetes. 58(10):2198-2210. (Oxylet-Physiocage, calorimetry, mouse, Canada)
  • Tai et al. (2009) Growth deficits in a postnatal day 3 rat model of hypoxic-ischemic brain injury. Behavioural Brain Research. 202:40-49. (rat neonate indirect calorimetry, USA)
  • Venditti P et al. (2009) T3 and the thyroid hormone β-receptor agonist GC-1 differentially affect metabolic capacity and oxidative damage in rat tissues. J. Exp. Biol. 212: 986-993. (indirect calorimetry, rat, Italy, USA).
  • Cordero P et al. (2008) Fat-to-glucose interconversion by hydrodynamic transfer of two glyoxylate cycle enzyme genes. Lipids in Health and Disease. 7:49 (indirect calorimetry, mouse, Spain)
  • Franckhauser S et al. (2008) Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice. Dialectologia. 51(7):1306-1316 (Physiocage, mouse, Spain)
  • Knauf et al. (2008) Brain Glucagon-Like Peptide 1 Signaling Controls the Onset of High-Fat Diet-Induced Insulin Resistance and Reduces Energy Expenditure. Endocrinology. 49(10):4768-4777 (mouse, France)
  • Bauche I et al. (2007) Overexpression of Adiponectin Targeted to Adipose Tissue in Transgenic Mice: Impaired Adipocyte Differentiation. Endocrinology 148(4): 1539-1549. (Energy expenditure, mice, France)
  • Cariou B (2007) FXR-deficiency confers increased susceptibility to torpor FEBS Letters, 581(27): 5191-5198. (Energy expenditure, mice, France, Netherlands)
  • Clerc P et al. (2007) Involvement of Cholecystokinin 2 Receptor in Food Intake Regulation: Hyperphagia and Increased Fat Deposition in Cholecystokinin 2 Receptor-Deficient Mice. Endocrinology 48(3): 1039-1049. (Energy expenditure, mice, France)
  • Ikeuchi M et al. (2007) Effects of Astaxanthin in Obese Mice Fed a High-Fat Diet. Bioscience, Biotechnology, and Biochemistry. 71(4): 893-899. (obesity, mice, Japan)
  • Prieto-Lloret J et al. (2007) Hypoxia transduction by carotid body chemoreceptors in mice lacking dopamine D2 receptors. J. Appl. Physiol. 103: 1269-1275 (LE 400-4, mice, Spain)
  • Tiraby C et al. (2007) Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles. Diabetologia. 50(10): 2190-2199. (Energy expenditure, mice, France)
  • Valle A et al. (2007) Sex Differences in Brown Adipose Tissue Thermogenic Features During Caloric Restriction. Cell. Physiol. Biochem. 19:195-204. (Rat, Spain).
  • Franckhauser S et al. (2006) Adipose Overexpression of Phosphoenolpyruvate Carboxykinase Leads to High Susceptibility to Diet-Induced Insulin Resistance and Obesity. Diabetes 55:273-280. (Energy expenditure, mice, Spain)
  • Bienvenu G et al. (2005) Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain. Diabetologia. 48(6): 1189-1197. (O2 consumption, mice, France)
  • Prieto-Lloret J et al. (2003) Ventilatory responses and carotid body function in adult rats perinatally exposed to hyperoxia. J. Physiol. 154: 126-144 (LE 400-4, spirometry, rat, Spain)

 

How to order

METABOLISM Software 

METABOLISM V3.0

76-0080

760080

Metabolism Software Platform (up to 32 enclosures). Needs Metabolism Experimental Modules for Calorimetry, food & drink intake and/or associated activity and rearing respectively.

METAOXY

76-0145

760145

Metabolism Software Experimental Module - Calorimetry (respiratory metabolism)

METAINT

76-0081

760081

Metabolism Software Experimental Module - Food & Drink Intake Monitoring

METAACT

76-0087

7-0087

Metabolism Software Experimental Module - Activity and rearing recording

How to order

Please contact our local delegates or contact us directly for receiving a quote.

 

Key features

  • Homecage (Physiocage) and Treadmill experiments
  • Modular software
  • Runtime viewers and charts for real time monitor
  • Calculates data in user-defined intervals of time
  • Numeric data table and plots available during data acquisition and analysis
  • Meal pattern analysis

 

 

 
 
 
 
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