For thermal analgesia and nociception

Key features
How to order


The Thermal Gradient Test has been described in Moqrich et al. 2005, and is one of the very few thermal nociception tests to be operator independent on freely moving rodents (mice and rat). A continuous temperature gradient (-4 to 65°C) is established over a 120 cm long base plate, on which the animal is free to walk. After the exploration period the rodent (mouse or rat) shows a distinct zone preference, or comfort zone.

Bioseb has defined an automated instrument for your research on analgesia and nociception (especially suitable for research on alodynia), with a temperature gradient stable over the surface and over time, allowing to identify the preferred temperature zone. Two instruments models will test independently and simultaneously 2 mice or small rats (1 adult rat).

The accompanying software, coupled to a video camera, displays for each animal the time spent per time period in each temperature zone, together with overall travelled distance.

The encrypted data and the video images are recorded synchronously in real time during the nociception experiments. This allows the operator to replay and check the animal behaviour at any time and remotely, and also to comply with Good Laboratory Practice (GLP).




Overall Dimensions (L x W x H)

2 mice/1 rat 139 x 30 x 40 cm (54.7 x 11.8 x 15.6 in)

Overall Weight

2 mice/1 rat 25 kg (33.1 lbs)

Power Supply

110/220 VAC

Number of Lanes (TGT2)

2 Mice/1 Rat

Lane Dimensions

2 mice/1 rat 125 x 10 x 15 cm (49.2 x 3.9 x 5.9 in)

Temperature Range

-4 to 65° C at plate surface, 20 to 25°, 50% RH at environment

Temperature Stability

1°C surface, over time

System Material

Base Plate: Aluminum alloy, Walls: Grey PPC, Top Cover: Transparent PPC

Software TGS

Allows to measure per animal: up to 20 temperature zones, time spent/temp.Zone/ time period, overall distance travelled.

Results: .xls type, presented per time periods. Raw data encrypted (glp) with video recording (synchronous).

Replay: at any time

Computer Requirements

PC 1GO Ram, Fast processor, Windows 7 or higher, 3 x USB port

How to order

Thermal Gradient system



Thermal Gradient test – 2 Mice/1 Rat, incl software, camera & support and Infrared thermometer for calibration



Kit to upgrade gradient to T2CT test


How to order

Please contact our local delegates or contact us directly for receiving a quote.


Key features

  • Continuous thermal gradient established over a 120 cm long base plate
  • Monitor 2 mice or 1 rat


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