Open-field test for basal global activity

Description
Related Panlab Integrated Solutions

Description

Open-field experiment allows the evaluation of animal’s basal activity and its evolution along the time, in response to novelty or anxiogenic environment, and in response to pharmacological treatment, lesion or genetic modification.

Basal locomotor activity is generally assessed in a specific activity arena (can be an open-field or others) for short-time/intermittent periods (<1h). Locomotion (horizontal activity), exploration (rearing and objects sniffing) and stereotypies (movements without displacement) are then recorded manually or using various automated procedures (photocell beams, video-tracking system, weight transducers…).

Related Panlab Integrated Solutions


IR ACTIMETER (Panlab) – SINGLE frame – (n) rats and normal adult mice 

Recommended solution for long-lasting experiments (>1h duration) and for evaluating several subject at the same time (up to 32subjects). This solution can be used for both rat and normal adult mice. Global activity data are provided for horizontal locomotor activity OR vertical activity (rearing) and for each user-defined interval of time. The data can be memorized and visualized in the LE8825 control unit allowing the use of the system without any computer. The SEDACOM or ACTITRACK software are needed for further data analysis and data report exportation to Excel. SEDACOM provides total global activity data and ACTITRACK provides additional data related to animal tracking and position. 

 


IR ACTIMETER (Panlab) – DOUBLE frame – (n) rats and normal adult mice 

This solution can be used for both rat and normal adult mice. Global activity data are provided for BOTH horizontal locomotor activity and vertical activity (rearing) and for each user-defined interval of time. The data can be memorized and visualized in the LE8825 control unit allowing the use of the system without any computer. The SEDACOM or ACTITRACK software are needed for further data analysis and data report exportation to Excel. SEDACOM provides total global activity data and ACTITRACK provides additional data related to animal tracking and position.

 


IR ACTIMETER (Panlab) – SINGLE frame – (n) small mice 

This solution can be used for both rat and normal adult mice. Global activity data are provided for horizontal locomotor activity OR vertical activity (rearing) and for each user-defined interval of time. The data can be memorized and visualized in the LE8825 control unit allowing the use of the system without any computer. The SEDACOM or ACTITRACK software are needed for further data analysis and data report exportation to Excel. SEDACOM provides total global activity data and ACTITRACK provides additional data related to animal tracking and position.

 


IR ACTIMETER (Panlab) – DOUBLE frame – (n) small mice 

This solution can be used for both rat and normal adult mice. Global activity data are provided for BOTH horizontal locomotor activity and vertical activity (rearing) and for each user-defined interval of time. The data can be memorized and visualized in the LE8825 control unit allowing the use of the system without any computer. The SEDACOM or ACTITRACK software are needed for further data analysis and data report exportation to Excel. SEDACOM provides total global activity data and ACTITRACK provides additional data related to animal tracking and position.

 


IR ACTIMETER (Panlab) – DOUBLE frame – 2 rats or 2 normal adult mice in (n) boxes

This solution can be used for both rat and normal adult mice. Two subjects can be placed into each actimeter box separated by the arena divider. The ACTITRACK software is needed for this solution, providing BOTH horizontal and vertical activity data for each subject, separately.

 


TRUSCAN ACTIMETER (Coulbourn) 

The Coulbourn actimeter is also a flexible recommended option for basal locomtor activity studies. Additional options are available for place preference, conditioning freezing or light/dark test. Ask for more details.

 


OPEN-FIELD BOX – SMART VIDEO TRACKING (Panlab) – 1 rat or 1 mouse – Recommended package

  • 1 x open-field box (LE800S for 1 rat, LE800SC for 4 rats, LE802S for 1 mouse, LE802SC for 4 mice)
  • 1 x SMARTSUPER
  • 1 x SMARTOF open-field experimental module (option)
  • 1 x camera (CAMCOLORPAL recommended, ask for support)
  • 1 x camera support (CAMROOF recommended, ask for support)

Recommended option for short lasting basal activity experiments (<1h) for 1 or several subjects, each one in its own arena. This option provides the data related with the animal track as well as the possibility to record the image of the experiment. The SMARTSUPER package of the SMART video-tracking software contains the SMARTCS customizable experimental module allowing the user to carry out open-field experiments as well as any other user-defined experiment (water maze, plus maze etc…).

The SMARTOF module is an additional straightforward and time-saving option providing standard zone definition and already predefined report directly related to open-fields experiments.

The SMARTSUPER package of the SMART video-tracking software also contains the SMARTMA and SMARTTW extensions for tracking several subjects at the same time (each one in its own arena) and for the automated detection of animal vertical activity (rearing). With the SMARTTW module specific experimental conditions are needed for obtaining reliable data (ask for more details).

The SMART video-tracking can also be used with user’s own open-field box and other capacities are available (ask for more details). 

 


OPEN-FIELD BOX – SMART VIDEO TRACKING – 1 rat or 1 mouse – Cost-saving package

  • 1 x open-field box (LE800S for 1 rat or LE802S for 1 mouse)
  • 1 x SMART V3.0 platform
  • 1 x SMARTOF open-field experimental module
  • 1 x CONANAVUSB analog/USB adapter
  • 1 x camera (CAMCOLORPAL recommended, ask for support)
  • 1 x camera support (CAMROOF recommended, ask for support)

Recommended option for short lasting basal activity experiments (<1h) for 1 subject in 1 arena.

This option provides the data related with the animal track as well as the possibility to record the image of the experiment. The SMARTOF module is a straightforward and time-saving option providing standard zone definition and already predefined report directly related to open-fields experiments. Additional experimental modules will be needed for using the system for other experiments (can be specific modules or the flexible customizable module SMARTCS). 

Whether the user is interested in detecting animal vertical activity (rearing), the following extension is needed:

  • 1 x SMARTTW – reliable data needs specific experimental condition (ask for more details)

The SMART video-tracking can also be used with user’s own open-field box and other capacities are available (ask for more details).


 

 

Reasons for choosing this test

  • Free exploration paradigm
  • Widely used in literature
  • Easy-to-do (for inexperienced users)
  • Can be entirely automated
  • Sensitive for both rats and mice

Reasons for not choosing this test

  • Requires non-stressful conditions (habituation and low lighting conditions)
 
 
 
 
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