Radial maze test

Description
Related Panlab Integrated Solutions

Description

The radial-arm maze task takes advantage of the natural tendency of food-deprived rodents to learn and remember different spatial locations for food in an eight-arm radial maze.

The large choice of protocol configurations available in this task has been proven to be very useful in assessing neurobehavioral bases for learning and memory. In the procedure to assess spatial working memory, each arm of the maze is baited and repeat entries into an arm that has already been visited constitute a working memory error. In the procedure to assess reference memory, only some arms are baited at the beginning of the session. First entry into a non-baited arm constitutes a reference memory error, and repeated entries to baited and non-baited arms are defined as a working memory error.

Related Panlab Integrated Solutions


AUTOMATED RADIAL MAZE - MAZESOFT8 (Panlab)


RADIAL MAZE - SMART VIDEO TRACKING (Panlab)


AQUATIC RADIAL MAZE - SMART VIDEO TRACKING (Panlab)


 

Reasons for choosing this test

  • Sensitive for both rats and mice
  • Spatial memory and non-spatial memory, working and reference memory
  • Gives index of learning progression (evolution curves of performances)
  • Robust performance, can be tested across a large range of delays

Reasons for not choosing this test

  • Requires food deprivation that may represent a major drawback for its use in knock-out mice
  • Locomotor activity alterations can interfere with arms exploration
 
 
 
 
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