The forced swimming test is a relatively simplistic and widely used model for testing depression. The forced-swimming paradigm was originally adopted by Porsolt et al. (1978). Naïve rats and mice forced to swim in a transparent cylinder (aversive and confined environment) innately fight to escape the apparatus. Following failed attempts to escape, they become immobile (i.e. float), a behavior generally considered as despair or “depressive-like”. Prior treatment with antidepressants decreases the time spent immobile and increases the latency to reach the first immobility episode.
We provide several different sized transparent cylinders for the forced swimming test. All cylinders are made of Perspex Acrylic.
This Catalog lists the most innovative sample preparation technologies and CPK models. Harvard Apparatus offers a broad range of products for various applications at sample sizes of 5µl to 5ml that can be used for separating small or large molecules, e.g., nucleosides from proteins, desalting samples, concentrating biomolecules, cleaning up samples for mass spectrometry and for binding studies. These Advanced Products include packed tips, spin columns, filtration plates, disposable or re-usable dialysis products and equilibrium dialyzers, ElectroPrep systems and a full line of CPK Models offered exclusively by Harvard Apparatus. The patented 96-Well Dispo-Equilibrium Dialysis Plates are already the system of choice for accurate binding studies.
Harvard Apparatus’ comprehensive surgical catalog is dedicated to the needs of researchers assembling and maintaining a state-of-the-art surgical suite. From surgical instruments to vital signs monitors and ventilators, we have the tools and knowledge to ensure your procedures are successful.
Isolating cardiomyocytes via Langendorff (retrograde) heart perfusion is known to yield the greatest number of cardiomyocytes compared to methods such as tissue dissection and manual dissociation. Harvard Apparatus is your source for the Hugo Sachs cardiomyocyte isolation systems, designed specifically to provide the tools necessary for obtaining high yields of sterile cardiomyocytes.
Hugo-Sachs Elektronik and Harvard Apparatus have always provided top-notch, fully integrated physiology research systems. Continuing our tradition of innovation and high performance we are happy to unveil the next generation Isolated Heart Perfusion System for Small Rodent models, the new IH-SR. The new IH-SR features an expanded range of measurement capabilities and ease of use which breaks new ground in ex-vivo cardiac research.
The IPL method has been found to be invaluable in characterizing the non-respiratory capabilities of pulmonary tissues such as pulmonary metabolic activity as well as the activities of various components (pulmonary alveolar macrophage, alveolar tissue, endothelial tissue, etc) in response to inhaled/airborne particulates/therapies. Isolated lung systems are equally useful for evaluating respiratory functions such as respiratory mechanics and gas exchange.
Harvard Apparatus and affiliates are cited over 850,000 times in 'Google Scholar', and over 10,000 times in 2012 alone. The following booklet contains examples of Harvard Apparatus products used in Neuroscience Research, along with summarizations of the experiments and related published articles.
Overview of Harvard Apparatus' complete anesthesia systems. Includes tabletop systems for active and passive scavenging, mobile systems for passive scavenging, and associated vaporizers and filter canisters.