DARK LIGHT box

For evaluating anxiety in rodents

Description
Key features
Specs
How to order
Publications

Description

The Panlab dark-light box allows easy and quick evaluation of the animal anxious behavior and its modification by pharmacological agents by assessing the animal displacements in two compartments with different size, color and illumination.

The dark-light experimental box, constructed of Perspex, is composed of a small black compartments and a big white compartment separated by a connecting gate. Each compartment has its own removable Perspex floor of the same color of the respective walls and 90 X 90 mm sectors delimited by lines. The compartments are independently illuminated: the white one with a 100 W white bulb and the black one with a 40 W red bulb. Both bulbs are 370 mm from the floor of the box.

The Panlab dark-light box can be supplied with a weight transducer system for automated animal detection. In that case, the automated experimental chambers (up to 8) are associated to the PC-based control software PPCWIN for data storage and analysis.

Even though it may represent a more complex experiment to set due to the strong lighting contrast existing between the compartments, some researchers also use the box with a video tracking system.

 

Specs

Chamber Dimensions - Mouse White compartment: 250 (D) x 250 (W) x 240 (H) mm; Black compartment: 160 (D) x 250 (W) x 240 (H) mm; Door: 70 x 70 mm
Chamber Dimensions - Rat White compartment: 310 (D) x 310 (W) x 240 (H) mm; Black compartment: 200 (D) x 310 (W) x 240 (H) mm; Door: 100 x 100 mm

Publications

  • Baeta-Corral R et al. (2013) Bizarre behaviors and risk assessment in 3xTg-AD mice at early stages of the disease. Behavioural Brain Research, Behav Brain Res. 2014 Jan 1;258:97-105(mouse, Spain)
  • Carrier N et al. (2013) Sex differences in the antidepressant-like effects of ketamine. Neuropharmacology. 2013 Jul;70:27-34. (rat, USA)
  • Carrier N et al. (2012) Testosterone and imipramine have antidepressant effects in socially isolated male but not female rats. Horm Behav. 2012 May;61(5):678-85. (rat, USA)
  • Leconte C et al. (2012) Repeated mild hypoxic exposures decrease anxiety-like behavior in the adult mouse together with an increased brain adrenomedullin gene expression. Behavioural Brain Research, Volume 230, Issue 1, 21 April 2012, Pages 78–84. (mouse, France)
  • Leconte C et al. (2011) Comparison of the effects of erythropoietin and its carbamylated derivative on behaviour and hippocampal neurogenesis in mice. Neuropharmacology, Volume 60, Issues 2–3, Pages 354–364. (mouse, France)
  • Gimenez-llort L el al. (2010) Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice. International Journal of Alzheimer's Disease, Volume 2010 (2010), Article ID 128354, 17 pages (mouse, Spain)
  • Lopez-Aumatell R et al (2007) Fearfulness in a large N/Nih genetically heterogeneous rat stock: Differential profiles of timidity and defensive flight in males and females. Behav. Brain Res. 188(1):41-55 (rat, Spain)
  • Lelong-Boulouard V et al. (2006) Interactions of buprenorphine and dipotassium clorazepate on anxiety and memory functions in the mouse. Drug and Alcohol Dependence, Volume 85, Issue 2, Pages 103–113 (mouse, France)
  • Gimenez-llort L el al. (2002) Mace lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate. Eur. J. Neurosci. 16(3): 547. (mice, Spain, Sweden)

 

How to order

STANDARD DARK-LIGHT BOX 

LE810

76-0007

Experimental chamber for mouse

LE812

76-0009

Experimental Chamber for rat

 

AUTOMATED DARK-LIGHT BOX 

LE816

76-0008

Automated experimental chamber for mouse with weight transducer

LE818

76-0010

Automated experimental chamber for rat with weight transducer

PPCWIN

76-0011

Software for Chamber control and Data Analysis (up to 8 units)

 

OTHER SOFTWARE OPTIONS  

SMART 3.0

 

SMART 3.0 video-tracking for the automated evaluation of behavior (see SMART3.0 product for detailed ordering information)

 

How to order

Please contact our local delegates or contact us directly for receiving a quote.

 

Key features

  • Compartments with independent and highly contrasted illumination
  • Associated with weight transducer technology for optimal animal detection
  • Easy to clean between two trials
  • Easy connection to a PC through RS232 port

 

 
 
 
 
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